カムルセパは、カネシュの最古のテキストですでに記録されている<ref>Haas, 2015, p439</ref>。後に行われたヒッタイトの儀式では、彼女とこの街との結びつきが残された<ref>Taracha, 2009, p30</ref>。また、疫病が流行しないようにとの祈願文から、タニワンダ(Taniwanda)も関連していることが判明した<ref>Singer, Hoffner, 2002, p134</ref>。神殿に座し、神話にも登場するにもかかわらず、彼女に関連する具体的な儀式や祭りについてはほとんど情報がない<ref>Taracha, 2009, pp114-115</ref>。
カムルセパの地位はルウィの神々の中でも高かった<ref>Taracha, 2009, p58</ref>。
Her status was also high in Luwian religion.{{sfn|Taracha|2009|p=58}} Piotr Taracha notes that there most likely was no single uniform Luwian pantheon, but certain deities, including Kamrušepa, as well as [[Tarḫunz|Tarhunt]], [[Tiwaz (Luwian deity)|Tiwad]], [[Maliya]], [[Arma (deity)|Arma]], [[Iyarri]], [[Sandas|Santa]] and a variety of tutelary gods represented by the logogram [[Lamassu|LAMMA]] were worshiped by most Luwian communities.{{sfn|Taracha|2009|p=107}} She is especially well attested in Luwian incantations from [[Kizzuwatna]].{{sfn|Frantz-Szabó|1980|pp=351-352}}
While she is one of the best attested goddesses in the Hittite pantheon of the [[Bronze Age]], there is presently no evidence for her worship continuing in the first millennium BCE.{{sfn|Lanaro|2015|p=86}}